Author(s)

Lei Jia, Bao Liling

Corresponding Author

Lei Jia

Abstract

To study the clinical effect of preventing wound infection at different times in general surgery with antibiotics. This paper reviews the clinical data of 479 cases of preventive antibiotic surgery treated in our hospital from December 2016 to December 1818. According to the time of antibiotic prevention, the patients were divided into three groups, one hour to two hours before operation. 113 patients in this group were treated by group A. 189 patients in group B were given 0.5-1 hour before operation and 177 patients in group C after operation. To analyze the preventive application of general surgery and compare the infection status and prognosis of each group. Results The infection rate of type I incision and type II incision in group A was significantly lower than that in group B and C. The difference between the two groups was significant (P<0.05). The infection rate of incision and type II incision in group B was significantly lower than that in group C. The difference between the two groups was statistical significance (P<0.05). The melting time, wound infection time and hospitalization time in group A were significantly shorter than those in group B and C. The difference has statistical significance. The fever time, incision infection time and hospitalization time in group B were significantly shorter than those in group C (P<0.05). The use of prophylactic antibiotics in general surgical patients 1-2 hours before operation significantly reduced incision infection rate, shortened fever and hospitalization time, and reduced treatment costs, which indicated that it was worth popularizing in clinical practice.

Keywords

General surgery, antibacterial drugs, preventive drugs, wound infection