Author(s)

Feng Chen, Zhen Tian

Corresponding Author

Feng Chen

Abstract

In recent years, an important reason for little knowledge about the pathogenesis of PM is the lack of suitable animal models. This paper has successfully induced experimental autoimmune myositis models by immunizing animals with sarcoplasmic globulin extracted from skeletal muscle of increased doses of skeletal muscle and inoculation with PT. The model has the advantages of short time consumption and high repetition rate. This provides a good experimental tool for studying idiopathic inflammatory myopathy and exploring new treatments.

Keywords

Th17 Cells, Idiopathic Dermatomyositis, Induced Myocardial Damage