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Web of Proceedings - Francis Academic Press
Web of Proceedings - Francis Academic Press

Effect of Folic Acid Level in Pregnant Women Serum on Pregnancy Outcome

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DOI: 10.25236/iccse.18.033

Author(s)

Weibin Guo, Lihua Sun, Lizhu Liang, Deyi Han

Corresponding Author

Lihua Sun

Abstract

Objective: To investigate the effect of folic acid level in pregnant women's serum on pregnancy outcome. Methods: 1321 pregnant women were selected from the gynecological clinic of our hospital from January 2013 to June 2018. The gestational age was between 26 and 40 weeks. Of these, 198 were pregnant women with poor pregnancy outcomes and 1123 were pregnant women with normal pregnancy outcomes. Twenty-four pregnant women with neural tube disease were selected as experimental group, and 30 pregnant women with normal fetus were selected as control group. The serum levels of folic acid in pregnant women with fetal neural tube diseases were compared with those of normal pregnant women. Results: There was no significant difference in homocysteine between the experimental group and the control group (P > 0.05), but the level of serum folic acid in the control group was significantly higher than that in the experimental group, and the level of folic acid in the normal pregnancy outcome was significantly higher than that in the unfavorable pregnancy outcome (P < 0.05). Conclusion: Serum Folic acid levels may increase the risk of neural tube defects and pregnancy outcomes.

Keywords

Pregnant Women, Folic Acid Level, Pregnancy Outcome, Neural Tube Defects