Meta-analysis of Cesarean Section and Bronchial Asthma in Children
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Objective: To investigate the relationship between cesarean section and bronchial asthma (asthma). Methods: The related literatures of cesarean section and asthma in Pubmed, China Knowledge Network, Wanfang Database and Chongqing Weipu Database were searched and RevMan was applied. 0 The software performs heterogeneity testing and effect value merging on documents that meet the inclusion criteria, along with sensitivity analysis and bias assessment. Results: A total of 8 relevant articles were included, including 32 622 in the asthma group and 890 876 in the control group. There was heterogeneity between the studies of cesarean section and asthma (P = 0. 000 4), so random effects models were used for analysis. The combined OR value (95% CI) for each study of cesarean section and asthma was 1. 22 (1. 10 ~ 1. 36), Z = 3. 76, P = 0. 0002. The sensitivity analysis results of each study were stable and there was no publication bias. Conclusion: Cesarean section is closely related to the occurrence of asthma.
Meta-Analysis, Cesarean Section, Bronchial Asthma, Children