Author(s)

Shuling Wang, Jianghong Hou, Tuanying Chen, Dongdong Shen

Corresponding Author

Shuling Wang

Abstract

Objective: To investigate the value of Shengjin Pingchuan Decoction and Qihuang Granule in the treatment of children with bronchiolitis. Methods: From July 2016 to October 2017, 106 children with bronchiolitis were enrolled in our hospital. According to the random number table method, the observation group and the control group were divided into 53 groups. On the basis of conventional treatment, the control group was treated with Qihuang Granules, and the observation group was treated with Qihuang Granule and Shengjin Pingchuan Decoction. Both groups were treated continuously for 7 days. The clinical efficacy, symptoms and signs of improvement and the changes of inflammatory index [TNF-α] levels before and after treatment were compared between the two groups. The patients were followed up for 6 months after the end of treatment, and the recurrence rate of the two groups was counted. Results: The total effective rate of the observation group was 92.45% (49/53), which was higher than that of the control group (77.36%, 41/53, P<0.05). The observation group had fever subsided, cough improved, wheezing relief, lung wet rales and wheezing sounds. The disappearance time was shorter than that of the control group (P<0.05). The levels of TNF-α in the two groups were lower than those before treatment (P<0.05), and the observation group was lower than the control group (P<0.05). The disease recurrence rate was 3.77% in the observation group. (2/53) was lower than the control group by 15.09% (8/53, P<0.05). Conclusion: Shengjin Pingchuan Decoction combined with Qihuang Granule in the treatment of children with bronchiolitis is effective, which can effectively promote the relief of symptoms and signs, may be related to the down-regulation of serum inflammatory factor expression, and also help to reduce the recurrence rate of the disease.

Keywords

Pediatric Bronchiolitis, Qihuang Granules, Shengjin Pingchuan Decoction, Symptom Improvement, Recurrence Rate