Author(s)

Hongxia Xie, Xin Pang, Xiaoyong Chen, Dongyang Li, Jianwei Zhang, Yan Zhang

Corresponding Author

Yan Zhang

Abstract

Objective: To investigate the efficacy and safety of Yishen Jianpi Qufeng Dehumification Decoction and Bailing Capsule in the treatment of chronic glomerulonephritis. Methods: Eighty-two cases of chronic glomerulonephritis were enrolled in our hospital from November 2015 to December 2017. The random number table was divided into control group (n=41) and study group (n=41). On the basis of routine intervention, the control group took Bai Ling capsules, and the study group added Yishen Jianpi Qufeng Dehumidification Decoction on the basis of the control group, all of which were treated for 3 months. The clinical efficacy, blood function urea nitrogen (BUN), serum creatinine (Scr), 24-hour urinary protein quantification, and incidence of adverse reactions were measured before and after treatment in both groups. Results: The total effective rate in the study group (92.68%) was higher than that in the control group (75.61%) (P<0.05); the BUN, Scr, and 24-hour urinary protein levels were lower in the study group than before the treatment, and the study group was lower than the control group. There was no significant difference between the incidence of adverse reactions in the study group (12.20%) and the control group (7.32%) (P>0.05). Conclusion: The combination of Bailing Capsule and Yishen Jianpi Qufeng Dehumification Decoction in the treatment of chronic glomerulonephritis can effectively improve the renal function of patients and improve the therapeutic effect of the disease. The incidence of adverse reactions is low and safe.

Keywords

Yishen Jianpi Qufeng Dehumidification Decoction, Bailing Capsule, Chronic Glomerulonephritis, Efficacy and Safety