Research on Effect of Guiping Tongqiao Decoction and Xinqi Granule on Symptoms Improvement and Serum Th1/Th2 Levels in Patients with Allergic Rhinitis
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Rui Wei, Muhua Liang
Objective: To investigate the application effect of Guiping Tongqiao Decoction combined with Xinqi Granules in patients with allergic rhinitis. Methods: Eighty-three patients with allergic rhinitis in our hospital were divided into two groups according to the random number table method. Both groups were treated with loratadine. 41 patients in the control group were given Xinqi granules on the basis of loratadine, and 42 patients were in the observation group. On the basis of the control group, Guiping Tongqiao Decoction was administered. The clinical efficacy, scores of symptoms before and after treatment (sneezing, nasal itching, runny nose), and the changes of serum immunoglobulin E (IgE) and Th1/Th2 levels were compared. And statistics the incidence of adverse reactions are in the two groups. Results: The total effective rate of the observation group was 95.24% (40/42), which was higher than 75.61% (31/41) of the control group (P<0.05). The symptoms of sneezing, nasal itching, salivation, and serum were observed in the observation group after 2 weeks of treatment. The level of lgE was lower than that of the control group, and the Th1/Th2 level was higher than that of the control group (P<0.05). The incidence of adverse reactions was 11.90% (5/42) in the observation group and 7.32% (3/41) in the control group. No statistical significance (P>0.05). Conclusion: Xinqi granules combined with Guiping Tongqiao Decoction can improve the serum lgE, Th1/Th2 levels in patients with allergic rhinitis, improve the clinical symptoms, and have good curative effect and high safety.
Allergic Rhinitis, Self-Made Guiping Tongqiao Decoction, Xinqi Granule