Author(s)

Qingming Liu, Hongyan Liu

Corresponding Author

Hongyan Liu

Abstract

The purpose of this study is to evaluate the effectiveness of glycyrrhizic acid preparations in combination with anti-tuberculosis drugs for treating pulmonary tuberculosis, as well as to assess their role in preventing hepatic damage in patients. A total of 3420 patients diagnosed with pulmonary tuberculosis at our hospital between January 1, 2024, and December 31, 2024, were included in the study. All patients received anti-tuberculosis treatment and were randomly assigned to two groups, with 1710 patients in each. The control group received glycohydroxylate preparation combined with anti-tuberculosis drugs, while the experimental group was given anti-tuberculosis drugs along with glycyrrhizic acid preparation. Recovery time for liver function abnormalities, overall treatment outcomes, and adverse reactions were analyzed. The experimental group demonstrated a shorter recovery time for liver function abnormalities, a higher total treatment effectiveness, and a lower rate of complications compared to the control group. These differences were statistically significant (P<0.05). The combination of glycyrrhizic acid preparations with anti-tuberculosis drugs facilitates faster recovery of liver function, enhances the clinical treatment response, and reduces the occurrence of complications in patients with pulmonary tuberculosis. This treatment approach is safe and reliable.

Keywords

Glycyrrhizic Acid Preparations; Anti-Tuberculosis Drugs; Combined Therapy; Pulmonary Tuberculosis; Therapeutic Effect; Hepatic Injury; Preventive Effect