The Effect of Laparoscopic Appendicitis Combined with Moroxynidazole on the Efficacy of Suppurative or Gangrenous Appendicitis and the Logistic Analysis of the Length of Stay
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Wenshi Lu, Qiaoli Yang, Tao Wu, Qiongyou Jing, Guoming Du
Objective: To study the effect of laparoscopic appendicitis combined with moroxynidazole on the efficacy of suppurative or gangrenous appendicitis and the logistic analysis of the effect on the length of stay. Methods: From June 2018 to April 2020, 120 patients with appendicitis treated in our hospital were randomly divided into two groups: the observation group and the control group, with 60 patients in each group. Laparoscopic appendectomy was performed in both groups. After the operation, the observation group and the control group were treated with malenidazole and ornidazole respectively. The treatment time was 1 Zhou. To compare the therapeutic effect, bacteriological evaluation, perioperative indexes and adverse reactions between the two groups, and to study the factors affecting the length of stay. Results: Compared with the control group, the clinical recovery rate of patients in the observation group was significantly higher, and there was no significant difference between the two groups in the number of anaerobic bacteria before treatment (P > 0.05).After treatment, the clearance number and clearance rate of patients in the observation group were significantly higher than those in the control group, and there was no significant difference between the two groups in the amount of bleeding during the bacteriostatic operation (P>0.05), The length of stay in the observation group was significantly lower than that in the control group (P < 0.05).There was no significant difference between the two groups in terms of transaminase elevation, platelet elevation, nausea, vomiting and ECG abnormalities during the treatment period (P > 0.05); male patients, age over 50 years old, appendix perforation, periappendiceal abscess, ornidazole use patients The number of days in hospital was significantly increased, and male patients, patients over 50 years old, appendiceal perforation, periappendiceal abscess, ornidazole use were independent risk factors for the increase of the number of days in hospital.Conclusion: Laparoscopic appendicitis combined with moroxynidazole has a significant effect on the treatment of suppurative or gangrenous appendicitis.At the same time, male patients, patients over 50 years old, appendiceal perforation, periappendiceal abscess and ornidazole use are all independent risk factors for prolonging the length of stay.
Laparoscopic appendectomy, Morpholinidazole, Risk factors, Length of stay