Study on the Mechanism of Sishen Wan's Anti-Irritable Bowel Syndrome
Download as PDF
Ying Mao, Geng Feng, Chunxue Yu, Shan Cong
Irritable bowel syndrome (IBS) refers to a group of clinical syndromes that include abdominal pain, bloating, changes in bowel habits, changes in stool characteristics, and mucous stools. It is persistent or recurrent, and can be caused by examination. These symptoms are organic diseases. This disease is the most common type of functional intestinal disease. The patients are mostly young and middle-aged, and the first onset is rare after the age of 50. The course of the disease is protracted and repeated, and the symptoms have long been troubled by patients, affecting the quality of life, and causing great psychological and economic burdens. At present, there is no special treatment for this disease. The author uses the classic traditional Chinese medicine Sishen Pill to treat patients with diarrhea-type irritable bowel syndrome, and has achieved good clinical results. The report is as follows. Objective: To observe the clinical effect of modified Sishen Pills in the treatment of diarrhea-type irritable bowel syndrome. Method: Sixty patients with diarrhea-type irritable bowel syndrome (spleen and kidney yang deficiency syndrome in TCM) were randomly divided into treatment group and control group. The treatment group was treated with Sishen Pills, and the control group was treated with Bifidobacterium Sanlian Live Bacteria Capsules. Use compound diphenoxylate tablets together, and observe the effect after 2 weeks of treatment. Results: Comparison of the scores of abdominal pain and diarrhea before and after treatment between the treatment group and the control group, the difference was statistically and significant (P <0.05); the treatment group and the control group had no statistically significant difference in the curative effect of abdominal pain and diarrhea (P > 0. 05); The treatment group and the control group have a statistically significant difference in the efficacy of TCM syndromes (P <0.05). Conclusion: Modified Sishen Pills can treat diarrhea-type irritable bowel syndrome (spleen-kidney yang deficiency syndrome in TCM). It has good curative effect in improving abdominal pain and diarrhea symptoms and TCM syndromes, and has no obvious adverse reactions.
Sishen pill, Irritable bowel syndrome, Mechanism, Drug effect