Author(s)

Shaotao Chen, Lin JIANG, Xiaolin Zhang, Mingjun Liu

Corresponding Author

Mingjun Liu

Abstract

To observe the anti-inflammatory effect of finger pressure method on obese rats with insulin resistance and study its mechanism. Methods: 20 male SD rats aged 5-8 weeks were randomly divided into two groups: general diet plus finger pressure method group and high fat plus finger pressure method group. They were fed with high fat diet for 8 weeks. The success of modeling was judged by fasting blood glucose, fasting insulin level and glucose tolerance test. The model of insulin resistance induced by obesity was induced by high fat diet for 8 weeks in the high fat plus finger pressure method group and the general diet plus finger pressure method group. After the experiment, blood glucose, blood insulin, TG, TCH, LDL and FFA were measured, and the fat-body ratio around testis and kidney was measured by killing animals. Results: The body weight, Lee index and fat coefficient of obese rats were significantly increased by high fat diet. Aerobic exercise and polysaccharide intervention can decrease the above morphological indexes. After 4 weeks of hypoxic exercise, the rats lost weight (P < 0.05), impaired glucose tolerance, insulin resistance and insulin sensitivity. The basic finger pressure method intervention can alleviate the anti-inflammation and improve the insulin resistance of obese rats. Conclusion: Finger pressing can reduce blood lipid, control obesity and improve insulin sensitivity.

Keywords

Finger pressure method; Insulin resistance; Obese rats