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Web of Proceedings - Francis Academic Press

The Liver Protection Effect of Different Polarity Fractions of Semen Astragali Complanati Wine on Mice

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DOI: 10.25236/icmbmm.2018.04


Xuehui Fan, Qingan Zhang, Chengrui Tian

Corresponding Author

Xuehui Fan


In this paper, healthy mice are exposed to different polarity extracts of semen astragali complanati wine, ether, ethyl acetate and water through intragastric administration for 30 days. Then the contents of superoxide dismutase (SOD), malonaldehyde (MDA), catalase (CAT), total antioxidant capacity (T-AOC), glutathione (GSH), glutathione peroxidase (GSH-PX) and protein carbonyl in rats' serum are detected, as well as the polyphone contents of different polarity extracts. The results show that semen astragali complanati wine and its different polarity extracts increase the antioxidant capacity of rats' liver. Rats from water extracts group have more polyphenol; but their antioxidant capacities are worse than rats from ether group and ethyl acetate group. Rats exposed to semen astragali complanati wine have the strongest antioxidant abilities. It indicates that compared with the low polarity extracts of ether and ethyl acetate, as well as the high polarity extract of water, diversified polarity extracts in the astragali complanati wine can produce synergistic effect, and help rats acquire better antioxidant capacity.


Semen astragali complanati wine, Mice, In vivo, Liver.