Author(s)

Ting Gao, Yanyan Miao and Mingsan Miao

Corresponding Author

Mingsan Miao

Abstract

The compatibility law of Jujubae fructus in zhongjing prescription is analyzed to provide reference for clinical medication and new prescription research and development. Methods: Based on the data of zhongjingfang which contains Chinese Jujubae fructus in treatise on febrile diseases and synopsis of the golden chamber, the compatibility rules of Chinese Jujubae fructus in zhongjingfang are statistically processed and analyzed by using Excel 2013 and SPSS Clementine 12.0 statistical software. Results: The treatise on febrile diseases contains 40 prescriptions of zhongjing containing Jujubae fructus, while the synopsis of the golden chamber contains 44 prescriptions of zhongjing containing Jujubae fructus. Among all zhongjing prescriptions included in the inclusion criteria, the top five Chinese medicine herbs with the highest cumulative frequency are Jujubae fructus (67 times, 100%), Glycyrrhizae radix et rhizoma (59 times, 88.06%), Zingiberis rhizoma recens (54 times, 80.60%), Cinnamomi ramulus (38 times, 56.72%), and Paeoniae radix alba (28 times, 41.79%). Based on the association rule analysis of zhongjing prescription with Chinese date, it is found that there are 13 pairs of combinations with the highest association intensity, and 11 pairs of combinations with the highest association intensity in the treatment of taiyang syndrome. Conclusion: Through the analysis of zhongjing prescription containing Jujubae fructus, the law of the compatibility of zhongjing Jujubae fructus with Zingiberis rhizoma recens and Glycyrrhizae radix et rhizoma is found to have a strong correlation with Jujubae fructus, and the combination of Jujubae fructus with different Chinese medicine is mostly used in taiyang disease syndrome and jueyin disease syndrome, which has a better therapeutic effect on diseases such as vomiting and retching, lung impotence, lung carbuncle cough and upper qi. Mathematical statistics is an important tool for the analysis of the law of Chinese medicine drug use, which provides modern research direction for guiding clinical drug use.

Keywords

Zhongjing; Jujubae Fructus; Rule of Medication; Association Rule