Author(s)

Zhu Peijing

Corresponding Author

Zhu Peijing

Abstract

The objective of this paper is to explore the influence of changes of coagulation system on pregnancy outcome and relationship between changes of coagulation system and premature delivery for parturients with hypertension of pregnancy before labor. The method of this paper is that 51 pregnant women with hypertension from July 2017 to July 2019 are selected as the observation group and 51 healthy pregnant women as the control group, and then they are researched.The results of this paper are that there was no significant change of coagulation function in 28 weeks of pregnancy and before parturition in control group (p＞0.05) . Fg and D-D levels in the observation group were significantly higher than those in the control group at 28th week of pregnancy (p＜0.05) , and were significantly much more higher than those in the control group from the 28th week of pregnancy to before birth (p＜0.05). The levels of them in PT, APTT and TT-III in the observation group were lower than those in the control group (p＜0.05). At the 28th week of pregnancy, there was a significant decline in the levels of them (p＜0.05) , and the difference was statistically significant. The neonatal weight of the observation group was significantly lower than that of the control group, and the neonatal asphyxia rate, fetal distress rate and perinatal mortality rate were significantly higher than those of the control group (p < 0.05) . The Cesarean section rate and preterm birth rate in the observation group were significantly higher than those in the control group (p＜0.05). The conclusion of this paper is that for pregnant women with hypertension, abnormal changes of coagulation system before delivery can lead to adverse pregnancy outcome and increase cesarean section rate and premature delivery rate.

Keywords

Gestational Hypertension; Coagulation System; Pregnancy Outcome; Premature Delivery