Author(s)

Hongwei Li, Yongqiong Wang, Man Zhang, Qilin Zhang

Corresponding Author

Qilin Zhang

Abstract

Recently, Streptococcus agalactiae (SA) has become a major pathogen leading to Streptococcosis. To understand the physiological responses of zebrafish (Danio rerio) to SA, the activity of antioxidant enzymes of the intestine (24 hours post-infection, hpi, respectively) in SA infected zebrafish were investigated. Glutathione-S-transferase (GST), glutathione peroxidase (GSH-Px), catalase (CAT), superoxide dismutase, and peroxidase activities, were employed as biochemical indicators. GST, GSH-Px, and CAT activity, significantly changed after SA infection (24 hpi vs control, p < 0.05) in the zebrafish intestine. This study is the first exploration for antioxidant enzyme activity under pathogenic infection in zebrafish intestine. Results suggest that the SA infection alters the antioxidant enzyme activity in zebrafish intestine.

Keywords

Zebrafish; intestine; Streptococcus agalactiae; Antioxidant enzyme activity