Author(s)

Jian Wang, Yan Duan, Changpeng Xu, Li Gong, Yu Zhang, Limin Cen, and Qiwen Sun

Corresponding Author

Jian Wang

Abstract

As a carrier of bone-targeting drug, liposome has a wide prospect with advantages of increasing the drug effect and less toxic by-effect. After modified by various mechanisms, liposome can carry drugs by active targeting, passive targeting and dual targeting etc. methods and deposits in bones to allow the drug selectively acts on the bone tissue. Currently the active targeting liposome is the key point of clinical study, which means to chemically modify the liposome surface in chemical way, and increase the bone-affinity of liposome. This study basing on the statement above, summarized the application of different liposome carrier drugs, and make a prospect of liposome application.

Keywords

Bone-targeting drug, Liposome carrier, Application study