Author(s)

Mingming Zhang, Huanqi Cui, Junjun Han, and Liangzhong Xu

Corresponding Author

Mingming Zhang

Abstract

In order to develop a new compound with novel structure and bactericidal activity. A series of 3,5-disubstituted-1,2,4-oxadiazole compounds containing pyrazole group were designed and synthesized. Their structures were confirmed by 1H NMR and HRMS, their bactericidal activity were evaluated by against rhizoctonia solani, gibberella zeae, botrytis cinerea and physalospora piricola. Preliminary bioactivity test results indicated that compound I6 showed the highest bactericidal activity among them, the inhibition rates of compound I6 against the above four fungi were 87.56, 88.69, 86.38, 89.78, respectively.

Keywords

Pyridine, Oxadiazole, Bactericidal activity