Author(s)

Yun Jie

Corresponding Author

Yun Jie

Abstract

Objective: To observe the application effect of atorvastatin combined with trimetazidine on myocardial ischemia. Methods: 140 patients with myocardial ischemia admitted in our hospital between August 2017 and August 2018 were randomly divided into two groups (experimental group and control group), 70 patients in each group. Patients in the experimental group were treated with atorvastatin and trimetazidine, while patients in the control group were treated with atorvastatin only. The therapeutic effects of the two therapeutic schedules were compared. Results: The total effective number of patients in the experimental group and the control group was 66 and 53 respectively, and the total effective rate of treatment was 94.28% and 75.71%, respectively. To the patients of the experimental group and the control group, their blood glucose level was (5.38±0.26) mmol/L and (6.17±1.99) mmol/L respectively; the total cholesterol level was (4.71±0.61) mmol/L and (4.88±0.75) mmol/L respectively, and the triglyceride level was (1.37±0.54) mmol/L and (1.49±0.78) mmol/L respectively. The patients suffering cardiovascular diseases in the experimental group and in the control group were 4 and 11 respectively, and the total incidence of cardiovascular disease was 5.71% and 15.71% respectively, P < 0.05. Conclusion: Treating patients suffering from myocardial ischemia with atorvastatin and trimetazidine can improve the efficiency of patients' treatment and effectively improve their blood lipid levels. It can also reduce the incidence of cardiovascular disease in patients, helps to shorten the disease course, improve the quality of life of patients and reduce the economic burden of these patients, and thereby this therapeutic schedule is worth applying in clinical treatment and promoting.

Keywords

Atorvastatin, Trimetazidine, Myocardial Ischemia, Application Effect