Author(s)

Zhanhao Hu

Corresponding Author

Zhanhao Hu

Abstract

It is challenging to employ conventional insulating biomaterials to repair the irreversible damage to the myocardial electrical conduction network induced by myocardial infarction, which may quickly result in arrhythmia and cardiac failure. Because of their conductivity and biocompatibility, composite materials based on conductive polymers have drawn attention from researchers studying cardiac healing. This article examines the common preparation techniques (solution blending, in-situ polymerization, and electrospinning) and examines how different techniques affect the materials' electrophysiological characteristics by controlling their microstructure (conductive particle dispersion, matrix-conductive phase interface bonding, fiber arrangement). This kind of material can achieve directional electrical conduction, low interface impedance coupling, or stable electrical signal transmission, encourage the synchronization of myocardial cell electrical activity, and aid in the repair of damaged myocardial electrical networks. This paper investigates and separates the relationship between preparation techniques and electrophysiological response, offering theoretical justification for the creation of bioelectric materials for cardiac repair and supporting the clinical management of myocardial damage.

Keywords

Conductive Polymer Based Composite Materials; Cardiac Tissue Repair; Preparation Method; Electrophysiological Response