Author(s)

Sufang Zhang

Corresponding Author

Sufang Zhang

Abstract

Objective: To investigate the result of high-flow nasal cannula humidification oxygen therapy (HFNC) on blood gas index and inflammation in patients with severe pneumonia complicated with respiratory failure. Methods: The clinical data of 60 patients with severe pneumonia complicated with respiratory failure in our hospital were selected and divided into experimental group (30 cases) and control group (30 cases) according to different oxygen therapy methods according to different oxygen therapy methods. The heart rate, respiratory rate, pH value, PaCO2, oxygenation index of the two groups before and 24 hours after treatment were compared, as well as the disappearance time of clinical symptoms and treatment efficiency after treatment. Results: Before treatment, there were no significant differences in heart rate, respiratory rate, pH value, PaCO2 and oxygenation index between the experimental group and the control group (all P > 0.05). After 24 hours of treatment, heart rate, respiratory rate, pH value, PaCO2 and oxygenation index of the experimental group were improved compared with those before treatment. The total effective rate of experimental group (100.0%) was higher than that of control group (40.0%). The difference was statistically significant (P < 0.05). Conclusion: The effect of high-flow nasal cannula humidification oxygen therapy in treating severe pneumonia complicated with respiratory failure is significant, which can effectively relieve the clinical symptoms and achieve good treatment effect.

Keywords

Acute respiratory failure, Humidification oxygen therapy with high-flow nasal cannula, Hfnc, Severe pneumonia complicated with respiratory failure