Author(s)

Xie Hongxia, Pang Xin, Zhang Yan

Corresponding Author

Zhang Yan

Abstract

To investigate the clinical efficacy and safety of urinary granules in assisting low-frequency hem perfusion combined with hemodialysis, and to explore the clinical effect and mechanism of the above treatments on pruritus in patients with uremia. METHODS: Ninety-nine patients who underwent renal medicine for uremia in February 2017 to December 1818 were enrolled in this study. The uremia patients were divided according to the diagnostic criteria for uremia and the order of admission to our hospital. For the two groups, among them, 45 patients in the control group were treated with low-frequency blood perfusion combined with hemodialysis; 45 patients in the observation group, based on the treatment method of the control group, and the treatment method of urinary granules. The gender and age of the control group and the observation group were analyzed and compared. There was no statistical difference (P>0.05), which had a high clinical promotion value. RESULTS: The pruritus symptoms of uremia patients before and after treatment in the control group and the observation group were regularly checked, and there were no significant differences in clinical indicators such as creatinine, uric acid, PTH, CRP and FGF-23. The clinical treatment effect of the observation group was obviously good. In the control group, it has significant curative effect on the treatment of pruritus in patients with uremia. Compared with the pre-treatment, the control group and the observation group have significant differences, indicating that urinary granules in assisting low-frequency hemoperfusion combined with hemodialysis in the treatment of uremia Patients with pruritus have a significant relief. After the observation group was treated with the combination of urinary granules and granules, calcium, FGF-23, PTH and phosphorus were significantly different from those before clinical treatment, which can effectively alleviate the symptoms of pruritus in uremic patients. There was no significant difference in the recurrence rate between the control group and the observation group. The pruritus of the observation group was lighter than that of the control group. Among them, the bone metabolism and renal function treatment were significantly better than the control group. Conclusion: Uremic granules have obvious curative effect on the symptoms of pruritus in patients with uremia treated by low-frequency hemoperfusion combined with hemodialysis, and can promote the recovery of renal function. In this clinical nursing study, the serum level of the uremia patients in the observation group was significantly lower than that in the control group, indicating that the urinary granules in the auxiliary low-frequency hemoperfusion combined with hemodialysis have a significant alleviation effect on the pruritus of uremic patients.

Keywords

Urinary Granules; Low-Frequency Blood Perfusion; Hemodialysis for Uremia; Skin Itching